Grem1em1(tdTomato,-icre/ERT2)Yil
Endonuclease-mediated Allele Detail
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| Symbol: |
Grem1em1(tdTomato,-icre/ERT2)Yil |
| Name: |
gremlin 1, DAN family BMP antagonist; endonuclease-mediated mutation 1, Omer Yilmaz |
| MGI ID: |
MGI:7624527 |
| Synonyms: |
Grem1-2A-tdTomato-2A-CreERT2 |
| Gene: |
Grem1 Location: Chr2:113579020-113588993 bp, - strand Genetic Position: Chr2, 57.43 cM
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| Alliance: |
Grem1em1(tdTomato,-icre/ERT2)Yil page
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| Allele Type: |
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Endonuclease-mediated (No functional change, Recombinase, Reporter) |
| Mutation: |
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Insertion
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Grem1em1(tdTomato,-icre/ERT2)Yil expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Grem1-2A-tdTomato-2A-iCreERT2 mouse was generated by inserting P2A-tdTomato-T2A-iCreERT2 cassette in the endogenous Grem1 gene locus immediately at the 5 end of the endogenous stop codon using CRISPR-Cas9 technology and zygote microinjection.
(J:347568)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Grem1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Grem1 Mutation: |
19 strains or lines available
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| Original: |
J:347568 Goto N, et al., Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury. Cell Stem Cell. 2022 Aug 4;29(8):1246-1261.e6 |
| All: |
1 reference(s) |
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Analysis Tools
