Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Grem1em1(EGFP,-Cre/ERT2)Yil
Name:	gremlin 1, DAN family BMP antagonist; endonuclease-mediated mutation 1, Omer Yilmaz
MGI ID:	MGI:7624527
Synonyms:	Grem1-2A-tdTomato-2A-CreERT2
Gene:	Grem1  Location: Chr2:113579020-113588993 bp, - strand  Genetic Position: Chr2, 57.43 cM
Alliance:	Grem1em1(EGFP,-Cre/ERT2)Yil page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (No functional change, Recombinase, Reporter) Mutation:    Insertion   Grem1em1(EGFP,-Cre/ERT2)Yil expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Grem1 (MGI:1344337)   Mutation details: Grem1-2A-tdTomato-2A-CreERT2 mouse was generated by inserting P2A-tdTomato-T2A-CreERT2 cassette in the endogenous Grem1 gene locus immediately at the 5 end of the endogenous stop codon using CRISPR-Cas9 technology and zygote microinjection. (J:347568)

Activity:	Tissue activity of this recombinase allele
Driver:	Grem1 (mouse) Summary of all recombinase alleles driven by Grem1. Alliance mouse Grem1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grem1 Mutation:	16 strains or lines available

Original:	J:347568 Goto N, et al., Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury. Cell Stem Cell. 2022 Aug 4;29(8):1246-1261.e6
All:	1 reference(s)