About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:291486 Daniel E, et al., Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560
Assay type: RNA in situ
MGI Accession ID: MGI:7623741
Gene symbol: Cyp26b1
Gene name: cytochrome P450, family 26, subfamily b, polypeptide 1
Probe: MGC clone 67317
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Fluorescein
Results
Specimen 1D: embryonic day 15.5 (more )
Note: Double labeled: green - Cyp26b1; red - Emcn (assay MGI:7623742) and Pecam1 (assay MGI:7623743).
Structure Cell Type Level Pattern Image Note
TS23: lung lung endothelial cell Present Punctate 1D Co-expression was detected with endothelial cell markers Pecam1/Emcn.
TS23: lung epithelium Weak Punctate 1D Immunopositive punctae were observed in some epithelial and stromal regions, but at much lower levels compared with endothelial cells.
TS23: lung stromal cell Weak Punctate 1D Immunopositive punctae were observed in some epithelial and stromal regions, but at much lower levels compared with endothelial cells.

Specimen 1H: embryonic day 15.5 (more )
Note: Double labeled: green - Cyp26b1; red - Emcn (assay MGI:7623742) and Pecam1 (assay MGI:7623743).
Structure Cell Type Level Pattern Image Note
TS23: metanephros endothelial cell Present Punctate 1H Co-expression was detected with endothelial cell markers Pecam1/Emcn.
TS23: metanephros epithelium Weak Punctate 1H Immunopositive punctae were observed in some epithelial and stromal regions, but at much lower levels compared with endothelial cells.
TS23: metanephros stromal cell Weak Punctate 1H Immunopositive punctae were observed in some epithelial and stromal regions, but at much lower levels compared with endothelial cells.

Specimen 5G: embryonic day 18.5 (more )
Note: Double labeled: green - Cyp26b1; red - Emcn (assay MGI:7623742).
Structure Cell Type Level Pattern Image Note
TS26: lung lung endothelial cell Present Punctate 5G Co-expression was detected with endothelial cell marker Emcn.

Specimen 5H: embryonic day 18.5; Cyp26b1em1Oncl/Cyp26b1em1Oncl (more )
Note: Double labeled: green - Cyp26b1; red - Emcn (assay MGI:7623742).
Structure Cell Type Level Pattern Image Note
TS26: lung lung endothelial cell Strong Punctate 5H Expression was strongly upregulated in mutant endothelial cells co-expressing Emcn.

Specimen S2F: embryonic day 18.5 (more )
Note: Double labeled: green - Cyp26b1; red - Lyve1 (assay MGI:7623744).
Structure Cell Type Level Pattern Image Note
TS26: lung endothelial cell of lymphatic vessel Present S2F' , S2F Co-expression with Lyve1 revealed that Cyp26b1 is also expressed in lymphatic endothelium in the lung.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/21/2024
MGI 6.23
The Jackson Laboratory