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Tg(Rr475-EGFP)#Slp
Transgene Detail
Summary
Symbol: Tg(Rr475-EGFP)#Slp
Name: transgene insertion, Samuel L Pfaff
MGI ID: MGI:7621867
Synonyms: MN(218-2)::GFP, tg(218-2::eGFP)
Transgene: Tg(Rr475-EGFP)#Slp  Location: unknown  
Alliance: Tg(Rr475-EGFP)#Slp page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsPutative miR218-2 promoter/enhancer sequence, 7442 bp genomic sequence upstream of Slit3 exon 6, was placed upstream of the enhanced green fluorescent protein gene, driving its expression in embryonic cranial motor nuclei and spinal motor columns. (J:227113)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:227113 Amin ND, et al., Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure. Science. 2015 Dec 18;350(6267):1525-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory