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Gene Expression Data
Assay Details
Assay
Reference: J:74183 Kieffer-Combeau S, et al., Cell-matrix interactions and cell-cell junctions during epithelial histo-morphogenesis in the developing mouse incisor. Int J Dev Biol. 2001 Sep;45(5-6):733-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7621249
Gene symbol: Dsg1a
Gene name: desmoglein 1 alpha
Antibody: anti-Desmoglein 1/2 (clone DG 3.10, 61002)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 6D: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: oral epithelium Present 6D
TS22: oral region Present Regionally restricted 6D Expression is in the vestibular lamina.
TS22: incisor epithelium Absent 6D

Specimen 6E: embryonic day 16.0 (more )
Note: Bell stage of tooth development.
Structure Level Pattern Image Note
TS24: stratum intermedium Strong Regionally restricted 6E , 6F Expression is in the stratum intermedium on the labial side of the incisor.
TS24: incisor epithelium Present Regionally restricted 6F , 6E On the lingual side there was expression in epithelial cells in contact with the inner dental epithelium.
TS24: inner enamel epithelium Weak 6F , 6E

Specimen 7D: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: basement membrane Strong Regionally restricted 7D Expression is in cells in contact with the basement membrane on the labial and lingual sides.
TS26: incisor epithelium Strong Regionally restricted 7D Expression is in cells in contact with the basement membrane on the labial and lingual sides.

Specimen 7E: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cervical loop Present Regionally restricted 7E Expression is in the lingual part of the cervical loop and is absent in the labial part.
TS26: incisor enamel organ Present Regionally restricted 7E Expression is in the lingual part of the cervical loop and is absent in the labial part.

Specimen 7F: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cervical loop Present Regionally restricted 7F Expression is in the lingual part of the cervical loop and is absent in the labial part.
TS26: incisor enamel organ Present Regionally restricted 7F Expression is in the lingual part of the cervical loop and is absent in the labial part.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory