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Gene Expression Data
Assay Details
Assay
Reference: J:107740 McGrath J, et al., Two populations of node monocilia initiate left-right asymmetry in the mouse. Cell. 2003 Jul 11;114(1):61-73
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7621236
Gene symbol: Pkd2
Gene name: polycystin 2, transient receptor potential cation channel
Antibody: YCC2
Detection system: Secondary antibody coupled to Texas Red
Results
Specimen 4B: embryonic day 7.75 (more )
Note: Double labeled: red - Pkd2; green - acetylated tubulin.
Structure Cell Type Level Pattern Image Note
TS11: node ciliated cell Present Regionally restricted 4C , 4B Expression was detected in all node monocilia, in addition to the cytoplasm. There was no left-right asymmetry in the expression pattern.
Specimen 4E: embryonic day 7.75; Pkd2tm2Som/Pkd2tm2Som (more )
Note: Double labeled: red - Pkd2; green - acetylated tubulin.
Structure Cell Type Level Pattern Image Note
TS11: node ciliated cell Absent 4F , 4E
Specimen 5A: embryonic day 7.75; Dnah11tm1.1Bknr/Dnah11tm1.1Bknr (more )
Note: Double labeled: red - Pkd2; green - Dnah11 reporter (assay MGI:7621216).
Structure Cell Type Level Pattern Image Note
TS11: node ciliated cell Present Regionally restricted 5C , 5I , 5F , 5G , 5A , 5D Expression was detected in node monocilia. Central, motile monocilia were labeled for both Pkd2 and Dnah11-GFP reporter. Peripheral, immotile cilia were labeled exclusively for Pkd2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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