Gene Expression Data
Assay Details
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Assay
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Reference:
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J:85847
Kokubu C, et al., Undulated short-tail deletion mutation in the mouse ablates Pax1 and leads to ectopic activation of neighboring Nkx2-2 in domains that normally express Pax1. Genetics. 2003 Sep;165(1):299-307
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7620539
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Gene symbol:
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Nkx3-2
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Gene name:
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NK3 homeobox 2
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Probe:
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Bapx1 probe3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
5A:
embryonic day 10.5
(more  )
Specimen
5A:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
5B:
embryonic day 10.5; Pax1Un-s/Pax1 +
(more )
Specimen
5B:
(close )
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Genetic Background:
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B6.CC57BR-Pax1Un-s
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Mutant Allele(s):
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Pax1Un-s/Pax1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: sclerotome |
Present |
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5B
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A slight reduction in expression was observed in heterozygotes, especially in the anterior part of the trunk - the cervical to thoracic regions.
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Specimen
5C:
(close )
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Genetic Background:
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B6.CC57BR-Pax1Un-s
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Mutant Allele(s):
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Pax1Un-s/Pax1Un-s
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: sclerotome |
Weak |
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5C
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Staining in homozygotes was significantly reduced.
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Analysis Tools
