Tg(ITGAM-FCAR*R209L)1Rcmo
Transgene Detail
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| Symbol: |
Tg(ITGAM-FCAR*R209L)1Rcmo |
| Name: |
transgene insertion 1, Renato C Monteiro |
| MGI ID: |
MGI:7620434 |
| Synonyms: |
FcalphaRIR209L |
| Transgene: |
Tg(ITGAM-FCAR*R209L)1Rcmo Location: unknown
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| Alliance: |
Tg(ITGAM-FCAR*R209L)1Rcmo page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(ITGAM-FCAR*R209L)1Rcmo expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| human |
FCAR (2204) |
expresses the human FCAR a.1 isoform gene, containing a point mutation (arginine to leucine) at position 209 |
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Tg(ITGAM-FCAR*R209L)1Rcmo expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
ITGAM (3684) |
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Mutation details: Transgenic mice expresses the human FCAR a.1 isoform gene, containing a point mutation (arginine to leucine) at position 209 under the control of the 1.7-kb human ITGAM promoter.
(J:120833)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:120833 Kanamaru Y, et al., Fcalpha receptor I activation induces leukocyte recruitment and promotes aggravation of glomerulonephritis through the FcRgamma adaptor. Eur J Immunol. 2007 Apr;37(4):1116-28 |
| All: |
4 reference(s) |
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Analysis Tools
