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Gene Expression Data
Assay Details
Assay
Reference: J:330334 Zhang H, et al., The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance. Development. 2022 Oct 1;149(19):dev200497
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7620155
Gene symbol: H2ax
Gene name: H2A.X variant histone
Results
Specimen 2J WT (upper): postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: ovary Ambiguous 2J WT (upper) Expression in wild type was not reported.
Specimen 2J WT (lower): postnatal week 6 (more )
Structure Level Pattern Image Note
TS28: ovary Ambiguous 2J WT (lower) Expression in wild type was not reported.
Specimen 2J Rtcb oo-/- (upper): postnatal week 6; Rtcbtm1Hyfn/Rtcbtm1Hyfn, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: ovary antral follicle Present Regionally restricted 2J Rtcb oo-/- (upper) Obvious DNA damage in more than 50% of oocytes in secondary and antral follicles.
TS28: ovary secondary follicle Present Regionally restricted 2J Rtcb oo-/- (upper) Obvious DNA damage in more than 50% of oocytes in secondary and antral follicles.
Specimen 2J Rtcb oo-/- (lower): postnatal week 6; Rtcbtm1Hyfn/Rtcbtm1Hyfn, Tg(Gdf9-icre)5092Coo/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: oocyte of antral follicle Present 2J Rtcb oo-/- (lower) Obvious DNA damage in more than 50% of oocytes in secondary and antral follicles.
TS28: oocyte of secondary follicle Present 2J Rtcb oo-/- (lower) Obvious DNA damage in more than 50% of oocytes in secondary and antral follicles.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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