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Gene Expression Data
Assay Details
Assay
Reference: J:298819 Jin C, et al., Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice. Sci Rep. 2020 Oct 28;10(1):18443
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7619783
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Antibody: anti-Ctip2
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2a P0 WT: postnatal day 0 (more )
Note: Double labeled: red - Bcl11b; green - Cux1 (assay MGI:7619782).
Structure Level Pattern Image Note
TS27: cortical layer V Strong 2a P0 WT (merged) , 2a P0 WT (enlarged) , 2a P0 WT Ctip2
TS27: cortical layer VI Weak 2a P0 WT (enlarged) , 2a P0 WT (merged) , 2a P0 WT Ctip2
Specimen 2a P0 Slc52a3-/-: postnatal day 0; Slc52a3tm2a(KOMP)Wtsi/Slc52a3tm2a(KOMP)Wtsi (more )
Note: Double labeled: red - Bcl11b; green - Cux1 (assay MGI:7619782).
Structure Level Pattern Image Note
TS27: cortical layer V Strong 2a P0 Slc52a2-/- (merged) , 2a P0 Slc52a2-/- (enlarged) , 2a P0 Slc52a2-/- Ctip2 All cortical layers were markedly thinner compared to wild type, but no difference in laminar formation
TS27: cortical layer VI Weak 2a P0 Slc52a2-/- (merged) , 2a P0 Slc52a2-/- Ctip2 , 2a P0 Slc52a2-/- (enlarged) All cortical layers were markedly thinner compared to wild type, but no difference in laminar formation
Specimen 5b SPL- P0 WT: postnatal day 0 (more )
Note: Double labeled: red - Bcl11b; green - Cux1 (assay MGI:7619782).
Structure Level Pattern Image Note
TS27: cortical layer V Strong 5b SPL- P0 WT Ctip2 , 5b SPL- P0 WT (merged)
TS27: cortical layer VI Weak 5b SPL- P0 WT (merged) , 5b SPL- P0 WT Ctip2
Specimen 5b SPL- P0 Slc52a3-/-: postnatal day 0; Slc52a3tm2a(KOMP)Wtsi/Slc52a3tm2a(KOMP)Wtsi (more )
Note: Double labeled: red - Bcl11b; green - Cux1 (assay MGI:7619782).
Structure Level Pattern Image Note
TS27: cortical layer V Strong 5b SPL- P0 Slc5a2-/- (merged) , 5b SPL- P0 Slc5a2-/- Ctip2
TS27: cortical layer VI Weak 5b SPL- P0 Slc5a2-/- Ctip2 , 5b SPL- P0 Slc5a2-/- (merged)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory