Gene Expression Data
Assay Details
Assay
|
Reference:
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J:67189
Shiojiri N, et al., Cell lineage analysis during liver development using the spf(ash)-heterozygous mouse. Lab Invest. 2001 Jan;81(1):17-25
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7619088
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Gene symbol:
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Otc
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Gene name:
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ornithine transcarbamylase
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Antibody:
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anti-OTC
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Detection system:
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Secondary antibody coupled to fluorescein
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Results
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Specimen
2C:
embryonic day 15.5
(more )
Specimen
2C:
(close )
Genetic Background:
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Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
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section
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Fixation:
|
Gendre's Fixative
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Embedding:
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Paraffin
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Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS23: intrahepatic bile duct epithelium |
|
Present |
|
2C
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Expression is in biliary epithelial cells and their progenitors.
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TS23: liver |
hepatoblast |
Present |
|
2C
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Expression is in hepatoblasts differentiating into hepatocytes in nonperiportal regions.
|
TS23: liver |
hematopoietic cell |
Absent |
|
2C
|
|
Specimen
2F:
embryonic day 17.5
(more )
Specimen
2F:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 17.5
|
Sex:
|
Not Specified
|
Type:
|
section
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Fixation:
|
Gendre's Fixative
|
Embedding:
|
Paraffin
|
Specimen
3D:
embryonic day 15.5
(more )
Specimen
3D:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Gendre's Fixative
|
Embedding:
|
Paraffin
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Specimen
3E:
embryonic day 17.5
(more )
Specimen
3E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 17.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Gendre's Fixative
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Embedding:
|
Paraffin
|
Specimen
4B:
embryonic day 15.5; Otcspf-ash/Otc +
(more )
Specimen
4B:
(close )
Genetic Background:
|
involves: C3H/He * C57BL/6
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Mutant Allele(s):
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Otcspf-ash/Otc+
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Age:
|
embryonic day 15.5
|
Sex:
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Female
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Type:
|
section
|
Fixation:
|
Gendre's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS23: liver |
hepatoblast |
Present |
Patchy |
4B
|
There is mosaic expression in hepatoblasts in nonperiportal regions.
|
TS23: intrahepatic bile duct epithelium |
|
Present |
Patchy |
4B
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There is mosaic expression in periportal bile duct progenitors.
|
TS23: liver |
hematopoietic cell |
Absent |
|
4B
|
|
Specimen
4D:
embryonic day 17.5; Otcspf-ash/Otc +
(more )
Specimen
4D:
(close )
Genetic Background:
|
involves: C3H/He * C57BL/6
|
Mutant Allele(s):
|
Otcspf-ash/Otc+
|
Age:
|
embryonic day 17.5
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
Gendre's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS25: liver |
hepatoblast |
Present |
Patchy |
4D
|
There is mosaic expression in hepatoblasts in nonperiportal regions.
|
TS25: intrahepatic bile duct epithelium |
|
Present |
Patchy |
4D
|
There is mosaic expression in periportal bile duct progenitors.
|
TS25: liver |
hematopoietic cell |
Absent |
|
4D
|
|
Specimen
5B:
embryonic day 15.5; Otcspf-ash/Otc +
(more )
Specimen
5B:
(close )
Genetic Background:
|
involves: C3H/He * C57BL/6
|
Mutant Allele(s):
|
Otcspf-ash/Otc+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
Gendre's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS23: liver |
hepatoblast |
Present |
Patchy |
5B
|
There is mosaic expression in hepatoblasts in nonperiportal regions.
|
TS23: intrahepatic bile duct epithelium |
|
Present |
Patchy |
5B
|
There is mosaic expression in periportal bile duct progenitors.
|
Specimen
5D:
embryonic day 15.5; Otcspf-ash/Otc +
(more )
Specimen
5D:
(close )
Genetic Background:
|
involves: C3H/He * C57BL/6
|
Mutant Allele(s):
|
Otcspf-ash/Otc+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Female
|
Type:
|
section
|
Fixation:
|
Gendre's Fixative
|
Embedding:
|
Paraffin
|
Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
TS23: liver |
hepatoblast |
Present |
Patchy |
5D
|
There is mosaic expression in hepatoblasts in nonperiportal regions.
|
TS23: intrahepatic bile duct epithelium |
|
Present |
Patchy |
5D
|
There is mosaic expression in periportal bile duct progenitors.
|
Specimen
not shown:
postnatal newborn
(more )
Specimen
not shown:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
postnatal newborn
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Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
Gendre's Fixative
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Embedding:
|
Paraffin
|
|