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Gene Expression Data
Assay Details
Assay
Reference: J:252079 McKee MD, et al., Compounded PHOSPHO1/ALPL deficiencies reduce dentin mineralization. J Dent Res. 2013 Aug;92(8):721-7
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7618592
Gene symbol: Alpl
Gene name: alkaline phosphatase, liver/bone/kidney
Antibody: ALPL antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1B: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible alveolar process osteoblast Present 1B More widely expressed in osteoblasts.
TS26: lower jaw molar enamel organ Present Regionally restricted 1B Expressed in some portions of the enamel organ, including the stellate reticulum, stratum intermedium, and outer dental epithelium.
TS26: outer enamel epithelium Present 1B
TS26: stellate reticulum Present 1B
TS26: stratum intermedium Present 1B
Specimen 1B inset: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: mandible alveolar process osteoblast Present 1B inset More widely expressed in osteoblasts.
Specimen 1D: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Present 1D
TS28: molar dental pulp odontoblast Strong Widespread 1D Strongly stained the entire odontoblast layer.
TS28: stratum intermedium Present 1D
Specimen 1F: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: molar dental pulp odontoblast Present 1F
TS28: stratum intermedium Present 1F
Specimen 1H: postnatal day 4 (more )
Structure Cell Type Level Pattern Image Note
TS28: dental alveolus osteoblast Present 1H
TS28: incisor dental pulp odontoblast Present 1H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory