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Gene Expression Data
Assay Details
Assay
Reference: J:201600 Cheng S, et al., Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice. Physiol Genomics. 2013 Oct 1;45(19):917-23
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7618579
Gene symbol: Sp7
Gene name: Sp7 transcription factor 7
Antibody: Anti-Sp7/Osterix antibody (ab22552)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to alkaline phosphatase
Results
Specimen 1B WT: embryonic day 18.0; Sp7tm2Crm/? (more )
Structure Cell Type Level Pattern Image Note
TS26: endochondral bone Present Regionally restricted 1B WT Expression was detected in the pre- and hypertrophic zones of the growth plate.
TS26: endochondral bone chondrocyte Present 1B WT
Specimen 1B KO: embryonic day 18.0; Sp7tm2Crm/Sp7tm2Crm, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: endochondral bone chondrocyte Weak 1B KO
Specimen 1C WT: postnatal week 3; Sp7tm2Crm/? (more )
Structure Cell Type Level Pattern Image Note
TS28: endochondral bone hypertrophic chondrocyte Present 1C WT
Specimen 1C Het: postnatal week 3; Sp7tm2Crm/Sp7+, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: endochondral bone hypertrophic chondrocyte Weak 1C Het
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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