Gene Expression Data
Assay Details
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Assay
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Reference:
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J:220406
Ishihara K, et al., Comparative proteomic profiling reveals aberrant cell proliferation in the brain of embryonic Ts1Cje, a mouse model of Down syndrome. Neuroscience. 2014 Dec 5;281:1-15
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7618518
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Gene symbol:
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Nme2
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Gene name:
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NME/NM23 nucleoside diphosphate kinase 2
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Antibody:
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anti-NME2
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
4A WT:
embryonic day 14.5
(more  )
Specimen
4A WT:
(close  )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
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4A WT
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Specimen
4A Ts1Cje:
(close )
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Genetic Background:
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involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub
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Mutant Allele(s):
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Ts(16C-tel)1Cje/0
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brain |
Present |
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4A Ts1Cje
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Specimen
4B WT:
embryonic day 14.5
(more )
Specimen
4B WT:
(close )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4B Ts1Cje:
(close )
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Genetic Background:
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involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub
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Mutant Allele(s):
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Ts(16C-tel)1Cje/0
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: ganglionic eminence |
Weak |
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4B Ts1Cje upper
,
4B Ts1Cje lower
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Expression decreased compared to wild type
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Specimen
4C WT:
embryonic day 14.5
(more )
Specimen
4C WT:
(close )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4C Ts1Cje:
(close )
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Genetic Background:
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involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub
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Mutant Allele(s):
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Ts(16C-tel)1Cje/0
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cerebral cortex |
Present |
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4C Ts1Cje
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Decreased expression marginally detected.
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Specimen
4D WT upper:
embryonic day 14.5
(more )
Specimen
4D WT upper:
(close )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4D Ts2Cje upper:
(close )
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Genetic Background:
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involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub
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Mutant Allele(s):
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Ts(16C-tel)1Cje/0
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cerebral cortex |
Present |
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4D Ts1Cje upper
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Decreased expression marginally detected.
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Specimen
4D WT lower:
embryonic day 14.5
(more )
Specimen
4D WT lower:
(close )
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Genetic Background:
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involves: C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
4D Ts1Cje lower:
(close )
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Genetic Background:
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involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub
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Mutant Allele(s):
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Ts(16C-tel)1Cje/0
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cerebral cortex |
Present |
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4D Ts1Cje lower
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Decreased expression marginally detected.
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Analysis Tools