Tmod2 Northern blot Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:83752 Cox PR, et al., Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory. Mol Cell Neurosci. 2003 May;23(1):1-12
Assay type:	Northern blot
MGI Accession ID:	MGI:7618358
Gene symbol:	Tmod2
Gene name:	tropomodulin 2

Probe:	Tmod2 probe
Probe preparation:	Double stranded DNA
Assay notes:	This assay was displayed as using A12 line (Tmod2<tm1Hzo>). Similar results were shown with the B3 line (Tmod2<tm2Hzo>).

Results

Image: 1C

	Sample Information		Bands		Other Sample Information
Lane	Age	Structure	9.5 kb (a)	9.3 kb (b)	Amount	Genetic Background	Mutant Allele(s)	Sex
-/-	P	TS28: brain	Absent	Present (c)	Not Specified; total RNA	involves: 129S7/SvEvBrd * C57BL/6J	Tmod2^tm1Hzo/Tmod2^tm1Hzo	Not Specified
+/-	P	TS28: brain	Present (d)	Present (d)	Not Specified; total RNA	involves: 129S7/SvEvBrd * C57BL/6J	Tmod2^tm1Hzo/Tmod2⁺	Not Specified
+/+	P	TS28: brain	Present	Absent	Not Specified; total RNA	involves: 129S7/SvEvBrd * C57BL/6J		Not Specified

Notes:
(a) Wild-type band.
(b) Mutant band, slightly smaller.
(c) A marked reduction ( about 82%) compared with the wild-type band.
(d) About 57% reduction compared with the wild-type band.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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