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Gene Expression Data
Assay Details
Assay
Reference: J:344337 Mishra A, et al., Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart. iScience. 2024 Jan 19;27(1):108748
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7610931
Gene symbol: Npr1
Gene name: natriuretic peptide receptor 1
Antibody: PGCA Antibody (PGCA-101AP)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C/D: embryonic day 11.5 (more )
Note: Double labeled: green - Npr1; red - Nppa (assay MGI:7610930).
Structure Level Pattern Image Note
TS19: left ventricle cardiac muscle Present Regionally restricted 1D , 1C The percentage of positive cells was 12.6-fold higher in the trabecular myocardium compared to the compact myocardium (72.7% vs. 12.8%, summarized in Fig 1I).

Specimen 1O: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: left ventricle cardiac muscle Present 1O Staining patterns in parallel sections indicated a clear overlap between Npr1/NPRA and Gja5/Cx40 expression in the primitive ventricular conduction system forming trabecular zones.

Specimen S1B/D: embryonic day 11.5 (more )
Note: Double labeled: green - Npr1; red - Nppa (assay MGI:7610930).
Structure Level Pattern Image Note
TS19: right ventricle cardiac muscle Present S1D , S1B The percentage of positive cells was significant higher in the trabecular myocardium compared to the compact myocardium.
TS19: interventricular septum cardiac muscle Present S1D , S1B The percentage of positive cells was significant higher compared to the compact myocardium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory