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Gene Expression Data
Assay Details
Assay
Reference: J:344233 Wu C, et al., Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis. Sci Rep. 2024 Jan 10;14(1):1047
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7610897
Gene symbol: Rbbp6
Gene name: retinoblastoma binding protein 6, ubiquitin ligase
Antibody: anti-P2P-R (sc-9962)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 8e RBBP6 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present Widespread 8e E13.5 DAPI/RBBP6 , 8e E13.5 RBBP6 Expression widely distributed in palatal mesenchyme and tongue.
TS21: tongue Present Widespread 8e E13.5 DAPI/RBBP6 , 8e E13.5 RBBP6 Expression widely distributed in palatal mesenchyme and tongue.
Specimen 8e RBBP6 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Regionally restricted 8e E14.5 DAPI/RBBP6 , 8e E14.5 RBBP6 Expression concentrated at medial edge epithelial seam.
Specimen 8e RBBP6 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: secondary palate Weak 8e E16.5 RBBP6 , 8e E16.5 DAPI/RBBP6 Reduced expression in palatal region.
TS24: maxilla Strong 8e E16.5 DAPI/RBBP6 , 8e E16.5 RBBP6 Increased expression in maxillary bone.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory