Prrt2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:299667 Calame DJ, et al., Presynaptic PRRT2 Deficiency Causes Cerebellar Dysfunction and Paroxysmal Kinesigenic Dyskinesia. Neuroscience. 2020 Nov 10;448:272-286
Assay type:	RNA in situ
MGI Accession ID:	MGI:7610585
Gene symbol:	Prrt2
Gene name:	proline-rich transmembrane protein 2

Probe:	Mm-Prrt2 (502661)
Probe preparation:	Antisense RNA

Results

4A +/+ ©

Specimen 4A +/+: postnatal (more

)
Note: Double labeled: green - Prrt2; red - Calb1 (assay MGI:7610586).

Structure	Cell Type	Level	Image	Note
TS28: cerebellum granule cell layer		Present	4A +/+
TS28: cerebellum Purkinje cell layer	Purkinje cell	Absent	4A +/+	No colocalization with calbindin was seen.
TS28: cerebellum molecular layer		Absent	4A +/+

4A -/- ©

Specimen 4A -/-: postnatal; Prrt2^{tm1d(KOMP)Wtsi}/Prrt2^{tm1d(KOMP)Wtsi} (more

)
Note: Double labeled: green - Prrt2; red - Calb1 (assay MGI:7610586).

Structure	Cell Type	Level	Image
TS28: cerebellum granule cell layer		Absent	4A -/-
TS28: cerebellum molecular layer		Absent	4A -/-
TS28: cerebellum Purkinje cell layer	Purkinje cell	Absent	4A -/-

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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