Prrt2 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:299667 Calame DJ, et al., Presynaptic PRRT2 Deficiency Causes Cerebellar Dysfunction and Paroxysmal Kinesigenic Dyskinesia. Neuroscience. 2020 Nov 10;448:272-286
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:7610563
Gene symbol:	Prrt2
Gene name:	proline-rich transmembrane protein 2

Reporter:	lacZ
	Direct Detection

Results

1A ©

Specimen 1A: postnatal; Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum	Present		1A

1B P7 ©

Specimen 1B P7: postnatal day 7; Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: deep cerebellar nucleus	Present		1B P7

1B P15 ©

Specimen 1B P15: postnatal day 15; Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum granule cell layer	Present		1B P15
TS28: deep cerebellar nucleus	Present		1B P15

1B P30 ©

Specimen 1B P30: postnatal day 30; Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum granule cell layer	Present		1B P30

1B P90 ©

Specimen 1B P90: postnatal day 90; Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum granule cell layer	Strong		1B P90

1C ©

Specimen 1C: postnatal; Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: hippocampus	Moderate	Regionally restricted	1C	Expressed in the posterior hippocampus.
TS28: brainstem	Moderate		1C

S2 ©

Specimen S2: postnatal adult; Prrt2^{tm1a(KOMP)Wtsi}/Prrt2^{tm1a(KOMP)Wtsi} (more

)
Note: Coronal sections from anterior to posterior brain.

Structure	Level	Pattern	Image	Note
TS28: cerebellum	Strong		S2
TS28: entorhinal cortex	Strong		S2
TS28: thalamus	Strong		S2
TS28: hippocampus	Moderate	Regionally restricted	S2	Expressed in the posterior hippocampus.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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