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Gene Expression Data
Assay Details
Assay
Reference: J:261178 Yousaf R, et al., Modifier variant of METTL13 suppresses human GAB1-associated profound deafness. J Clin Invest. 2018 Apr 2;128(4):1509-1522
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7610080
Gene symbol: Mettl13
Gene name: methyltransferase 13, eEF1A lysine and N-terminal methyltransferase
Antibody: anti-METTL13 (PB447)
Assay notes: Two Mettl13 were described, but the one used in this assay was not detailed. Anti-Mettl13(PB478) MGI:7610069 may have been used in this assay.
Results
Specimen 5 Cochlear duct: postnatal adult (more )
Note: Triple labeled: red - Mettl13; green - Gab1 (assay MGI:7610081); cyan - Nefh (assay MGI:7610082).
Structure Level Pattern Image Note
TS28: cochlear duct Present 5_ Cochlear duct METTL13 , 5_ Cochlear duct Merge
Specimen 5 Innervation: postnatal adult (more )
Note: Triple labeled: red - Mettl13; green - Gab1 (assay MGI:7610081); cyan - Nefh (assay MGI:7610082).
Structure Level Pattern Image Note
TS28: cochlea Present Regionally restricted 5_Innervation Merge , 5_Innervation METTL13 Expression co-colocalized with Gab1 and Nefh expression in nerve fibers innervating inner hair cells and outer hair cells in cochlear duct.
Specimen 5 Spiral ganglion: postnatal adult (more )
Note: Triple labeled: red - Mettl13; green - Gab1 (assay MGI:7610081); cyan - Nefh (assay MGI:7610082).
Structure Cell Type Level Pattern Image Note
TS28: cochlear ganglion spiral ganglion neuron Present Regionally restricted 5_Spiral ganglion METTL13 , 5_Spiral ganglion Merge Expression co-colocalized with Gab1 and Nefh expression in neural call bodies of spiral ganglion.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory