About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:254909 Lee JE, et al., Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis. Nat Commun. 2017 Dec 20;8(1):2217
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7608403
Gene symbol: Ucp1
Gene name: uncoupling protein 1 (mitochondrial, proton carrier)
Results
Specimen 1d Brd4f/f: embryonic day 18.5; Brd4tm1Kaig/Brd4tm1Kaig (more )
Note: Double labeled: green - Ucp1; red - myosin.
Structure Level Pattern Image Note
TS26: brown fat Present 1d Brd4f/f
TS26: skeletal muscle Present 1d Brd4f/f

Specimen d Brd4f/f; Myf5-Cre: embryonic day 18.5; Brd4tm1Kaig/Brd4tm1Kaig, Myf5tm3(cre)Sor/Myf5+ (more )
Note: Conditional mutant. Double labeled: green - Ucp1; red - myosin.
Structure Level Pattern Image Note
TS26: brown fat Present 1d Brd4f/f; Myf5-Cre This mutant has a severe reduction of brown fat and muscle mass.
TS26: skeletal muscle Present 1d Brd4f/f; Myf5-Cre This mutant has a severe reduction of brown fat and muscle mass.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/30/2025
MGI 6.24
The Jackson Laboratory