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Gene Expression Data
Assay Details
Assay
Reference: J:286599 Song NN, et al., Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199
Assay type: RNA in situ
MGI Accession ID: MGI:7608311
Gene symbol: Phox2b
Gene name: paired-like homeobox 2b
Results
Specimen 2C Phox2b Control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 2C Phox2b Control Expression in dorsal rhombomere 1.

Specimen 2C Phox2b Zc4h2 KO: embryonic day 10.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 2C Phox2b KO Expression not changed compared to control.

Specimen 2D Phox2b Control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 2D Phox2b Control

Specimen 2D Phox2b Zc4h2 KO: embryonic day 12.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 2D Phox2b KO No obvious alteration in expression compared to control.

Specimen 2E Phox2b Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 2E Phox2b Control

Specimen 2E Phox2b Zc4h2 KO: embryonic day 16.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Absent 2E Phox2b KO Expression not observed.

Specimen 3C Phox2b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 3C Phox2b

Specimen 3E Phox2b Control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 3E Phox2b Control Expression in dorsal rhombomere 1.

Specimen 3E Phox2b Rnf220 KO: embryonic day 10.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 3E Phox2b KO Expression similar to that of control.

Specimen 3F Phox2b Control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 3F Phox2b Control

Specimen 3F Phox2b Rnf220 IO: embryonic day 12.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 3F Phox2b KO Expression not obviously changed compared to control.

Specimen 3H Phox2b Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 3H Phox2b Control

Specimen 3H Phox2b Rnf220 KO: embryonic day 16.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Trace 3H Phox2b KO Expression hardly detected in locus coeruleus region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory