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Gene Expression Data
Assay Details
Assay
Reference: J:286599 Song NN, et al., Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199
Assay type: RNA in situ
MGI Accession ID: MGI:7608306
Gene symbol: Phox2a
Gene name: paired-like homeobox 2a
Results
Specimen 2C Phox2a Control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 2C Phox2a Control Expression in dorsal rhombomere 1.

Specimen 2C Phox2a Zc4h2 KO: embryonic day 10.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 2C Phox2a KO Expression not changed compared to control.

Specimen 2D Phox2a Control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 2D Phox2a Control

Specimen 2D Phox2a Zc4h2 KO: embryonic day 12.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS20: pons Weak 2D Phox2a KO Expression slightly reduced compared to control.

Specimen 2E Phox2a Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 2E Phox2a Control

Specimen 2E Phox2a Zc4h2 KO: embryonic day 16.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Absent 2E Phox2a KO Expression not observed.

Specimen 3C Phox2a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 3C Phox2a

Specimen 3E Phox2a Control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 3E Phox2a Control Expression in dorsal rhombomere 1.

Specimen 3E Phox2a Rnf220 KO: embryonic day 10.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 3E Phox2a KO Expression similar to that of control.

Specimen 3F Phox2a Control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 3F Phox2a Control

Specimen 3F Phox2a Rnf220 IO: embryonic day 12.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS20: pons Weak 3F Phox2a KO Expression reduced compared to control.

Specimen 3H Phox2a Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 3H Phox2a Control

Specimen 3H Phox2a Rnf220 KO: embryonic day 16.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Trace 3H Phox2a KO Expression hardly detected in locus coeruleus region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory