Gene Expression Data
Assay Details
Assay
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Reference:
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J:150356
Jacobs FM, et al., Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons. Development. 2009 Jul;136(14):2363-73
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7596518
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Gene symbol:
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Nr4a2
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Gene name:
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nuclear receptor subfamily 4, group A, member 2
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Probe:
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Nurr1 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
1A +/+ rostral:
embryonic day 14.5
(more )
Specimen
1A +/+ rostral:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
1A +/+ 1
|
Expressed in the mesodiencephalic dopamine neuronal field.
|
Specimen
1A +/+ middle:
embryonic day 14.5
(more )
Specimen
1A +/+ middle:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
1A +/+ 2
|
Expressed in the mesodiencephalic dopamine neuronal field.
|
Specimen
1A +/+ caudal:
embryonic day 14.5
(more )
Specimen
1A +/+ caudal:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
1A +/+ 3
|
Expressed in the mesodiencephalic dopamine neuronal field.
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Specimen
1A -/- rostral:
(close )
Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Nr4a2tm1Omc/Nr4a2tm1Omc
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Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
1A -/- 1
|
Truncated transcripts were still detected, showing patterning of the mesodiencephalic dopamine neuronal field except for the lateral-most population in the rostral part.
|
Specimen
1A -/- middle:
(close )
Genetic Background:
|
involves: 129S7/SvEvBrd
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Mutant Allele(s):
|
Nr4a2tm1Omc/Nr4a2tm1Omc
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Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
1A -/- 2
|
Truncated transcripts were still detected, showing patterning of the mesodiencephalic dopamine neuronal field except for the lateral-most population in the rostral part.
|
Specimen
1A -/- caudal:
(close )
Genetic Background:
|
involves: 129S7/SvEvBrd
|
Mutant Allele(s):
|
Nr4a2tm1Omc/Nr4a2tm1Omc
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
1A -/- 3
|
Truncated transcripts were still detected, showing patterning of the mesodiencephalic dopamine neuronal field except for the lateral-most population in the rostral part.
|
Specimen
4A:
embryonic day 14.5
(more )
Specimen
4A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
4A
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Expressed in the mesodiencephalic dopamine neuronal field.
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TS22: hypothalamus |
Present |
Regionally restricted |
4A
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Expressed in the hypothalamic nuclei, located anterior to the mesodiencephalic dopamine neuronal field.
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Specimen
5A:
postnatal adult
(more )
Specimen
5A:
(close )
Genetic Background:
|
Not Specified
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Age:
|
postnatal adult
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Sex:
|
Not Specified
|
Type:
|
section
|
Specimen
6A:
embryonic day 14.5
(more )
Specimen
6A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
6A
|
Expressed in the mesodiencephalic dopamine neuronal field.
|
Specimen
6A':
(close )
Genetic Background:
|
involves: 129S7/SvEvBrd
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Mutant Allele(s):
|
Nr4a2tm1Omc/Nr4a2tm1Omc
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
6A'
|
Truncated transcripts were still detected, showing patterning of the mesodiencephalic dopamine neuronal field except for the lateral-most population in the rostral part.
|
Specimen
6I:
embryonic day 14.5
(more )
Specimen
6I:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
6I
|
Expressed in the mesodiencephalic dopamine neuronal field.
|
Specimen
6I':
(close )
Genetic Background:
|
involves: 129S7/SvEvBrd
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Mutant Allele(s):
|
Nr4a2tm1Omc/Nr4a2tm1Omc
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
6I'
|
Truncated transcripts were still detected, showing patterning of the mesodiencephalic dopamine neuronal field except for the lateral-most population in the rostral part.
|
Specimen
7A:
embryonic day 14.5
(more )
Specimen
7A:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
7A
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Expressed in the mesodiencephalic dopamine neuronal field.
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Specimen
7A':
(close )
Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
|
Pitx3ak/Pitx3ak
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Age:
|
embryonic day 14.5
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Sex:
|
Not Specified
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Type:
|
section
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: midbrain |
Present |
Regionally restricted |
7A'
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Expressed in the mesodiencephalic dopamine neuronal field, similar as in the wild-type.
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Specimen
8K:
embryonic day 14.5
(more )
Specimen
8K:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
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Type:
|
section
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Specimen
8O:
embryonic day 14.5
(more )
Specimen
8O:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
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Sex:
|
Not Specified
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Type:
|
section
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Specimen
not shown:
(close )
Genetic Background:
|
involves: 129
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Mutant Allele(s):
|
Dlk1tm1Hsul/Dlk1tm1Hsul
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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