Lgr6 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:262420 Szenker-Ravi E, et al., RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6. Nature. 2018 May;557(7706):564-569
Assay type:	RNA in situ
MGI Accession ID:	MGI:7596255
Gene symbol:	Lgr6
Gene name:	leucine-rich repeat-containing G protein-coupled receptor 6

Results

Specimen 2h Lgr6/Rspo2 (upper): embryonic day 14.5 (more

)
Note: Double labeled: blue - Lgr6; pink - Rspo2 (assay MGI:7596266).

Structure	Level	Pattern	Image	Note
TS22: forelimb epidermis	Present	Regionally restricted	2h Lgr6/Rspo2 (upper)	Expression co-localized with Rspo2 in apical ectodermal ridge.

Specimen 2h Lgr6/Rspo2 l(ower): embryonic day 14.5 (more

)
Note: Double labeled: blue - Lgr6; pink - Rspo2 (assay MGI:7596266).

Structure	Level	Pattern	Image	Note
TS22: forelimb epidermis	Present	Regionally restricted	2h Lgr6/Rspo2 (lower)	Expression co-localized with Rspo2 in apical ectodermal ridge.

Specimen ED5f Lgr6/Rspo2 (upper): embryonic day 14.5 (more

)
Note: Double labeled: blue - Lgr6; pink - Rspo2 (assay MGI:7596266).

Structure	Cell Type	Level	Pattern	Image	Note
TS22: lung	smooth muscle cell	Strong	Regionally restricted	ED5f Lgr6/Rspo2 (upper)	Robust expression in smooth muscle cells.

Specimen ED5f Lgr6/Rspo2 (lower): embryonic day 14.5 (more

)
Note: Double labeled: blue - Lgr6; pink - Rspo2 (assay MGI:7596266).

Structure	Cell Type	Level	Pattern	Image	Note
TS22: lung	smooth muscle cell	Strong	Regionally restricted	ED5f Lgr6/Rspo2 (lower)	Robust expression in smooth muscle cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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