Isl1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:173396 Sang L, et al., Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13;145(4):513-28
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7596124
Gene symbol:	Isl1
Gene name:	ISL1 transcription factor, LIM/homeodomain

Antibody:	anti-Islet1/2
Detection system:	Secondary antibody coupled to Alexa Fluor

Results

Specimen 6H +/- Isl1: embryonic day 9.5; Tctn2^tm1.1Reit/Tctn2⁺ (more

)
Note: Double labeled: green - Isl1 and Isl2; red - Pax6 (assay MGI:7596127).

Structure	Level	Pattern	Image	Note
TS15: future spinal cord	Present		6H Isl1/2/Pax6 +/-

Specimen 6H -/- Isl1: embryonic day 9.5; Tctn2^tm1.1Reit/Tctn2^tm1.1Reit (more

)
Note: Double labeled: green - Isl1 and Isl2; red - Pax6 (assay MGI:7596127).

Structure	Level	Pattern	Image	Note
TS15: future spinal cord	Trace		6H Isl1/2/Pax6 -/-	Authors report severe reduction in expression in motor neurons.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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