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Gene Expression Data
Assay Details
Assay
Reference: J:209053 Hoekstra EJ, et al., Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons. Eur J Neurosci. 2013 Jan;37(1):23-32
Assay type: RNA in situ
MGI Accession ID: MGI:7595762
Gene symbol: Lmx1a
Gene name: LIM homeobox transcription factor 1 alpha
Probe: Lmx1a probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2S: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 2S Expressed in a large part of the mesodiencephalic dopamine neuronal field, although not in all cells.
Specimen 2X: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 2X Expressed in a large part of the mesodiencephalic dopamine neuronal field, although not in all cells.
Specimen 3A: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 3A Expressed in a large part of the mesodiencephalic dopamine neuronal field, although not in all cells.
Specimen 3J: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 3J Expressed in a large part of the mesodiencephalic dopamine neuronal field, although not in all cells.
Specimen 3S: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 3S Expressed in a large part of the mesodiencephalic dopamine neuronal field, although not in all cells.
Specimen 4C: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 4C More broadly expressed than TH.
Specimen 4D: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 4D More broadly expressed than TH.
Specimen 4G: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 4G More broadly expressed than TH.
Specimen 4H: embryonic day 14.5 (more )
Note: Double labeled: purple - Lmx1a; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 4H More broadly expressed than TH.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory