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Gene Expression Data
Assay Details
Assay
Reference: J:209053 Hoekstra EJ, et al., Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons. Eur J Neurosci. 2013 Jan;37(1):23-32
Assay type: RNA in situ
MGI Accession ID: MGI:7595758
Gene symbol: Ptp4a1
Gene name: protein tyrosine phosphatase 4a1
Probe: Ptp4a1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain Present Widespread 2H Expressed throughout the brain, and clearly overlapped with the mesodiencephalic dopamine neuronal field.

Specimen 2N: embryonic day 14.5 (more )
Note: Double labeled: purple - Ptp4a1; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: brain Present Widespread 2N Expressed throughout the brain, and clearly overlapped with the mesodiencephalic dopamine neuronal field. Slightly higher transcript levels were observed in the ventricular and intermediate zones.
TS22: midbrain ventricular layer Present 2N
TS22: brainstem nucleus Present Regionally restricted 2N Expressed in a specific group of cells located adjacent to the mesodiencephalic dopamine neuronal system, most likely in the red nucleus area, and did not overlap with TH or Lmx1a expression domains.

Specimen 2R: embryonic day 14.5 (more )
Note: Double labeled: purple - Ptp4a1; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: brain Present Widespread 2R Expressed throughout the brain, and clearly overlapped with the mesodiencephalic dopamine neuronal field. Slightly higher transcript levels were observed in the ventricular and intermediate zone.
TS22: midbrain ventricular layer Present 2R
TS22: brainstem nucleus Present Regionally restricted 2R Expressed in a specific group of cells located adjacent to the mesodiencephalic dopamine neuronal system, most likely in the red nucleus area, and did not overlap with TH or Lmx1a expression domains.

Specimen 3G: embryonic day 14.5 (more )
Note: Double labeled: purple - Ptp4a1; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: brain Present Widespread 3G Expressed throughout the brain, and clearly overlapped with the mesodiencephalic dopamine neuronal field. Slightly higher transcript levels were observed in the ventricular and intermediate zone.
TS22: midbrain ventricular layer Present 3G
TS22: brainstem nucleus Present Regionally restricted 3G Expressed in a specific group of cells located adjacent to the mesodiencephalic dopamine neuronal system, most likely in the red nucleus area, and did not overlap with TH or Lmx1a expression domains.

Specimen 3P: embryonic day 14.5 (more )
Note: Double labeled: purple - Ptp4a1; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: brain Present Widespread 3P Expressed throughout the brain, and clearly overlapped with the mesodiencephalic dopamine neuronal field. Slightly higher transcript levels were observed in the ventricular and intermediate zone.
TS22: brainstem nucleus Present Regionally restricted 3P Expressed in a specific group of cells located adjacent to the mesodiencephalic dopamine neuronal system, most likely in the red nucleus area, and did not overlap with TH or Lmx1a expression domains.
TS22: midbrain ventricular layer Present 3P

Specimen 3Y: embryonic day 14.5 (more )
Note: Double labeled: purple - Ptp4a1; brown - Th (assay MGI:7595776).
Structure Level Pattern Image Note
TS22: brain Present Widespread 3Y Expressed throughout the brain, and clearly overlapped with the mesodiencephalic dopamine neuronal field. Slightly higher transcript levels were observed in the ventricular and intermediate zones.
TS22: midbrain ventricular layer Present 3Y


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory