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Gene Expression Data
Assay Details
Assay
Reference: J:220849 Achilleos A, et al., MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development. Hum Mol Genet. 2015 May 15;24(10):2884-98
Assay type: RNA in situ
MGI Accession ID: MGI:7593903
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: unsegmented mesenchyme Strong Regionally restricted 5C Strong expression restricted to posterior-most region of presomitic mesoderm.
Specimen 5D,D': embryonic day 10.5 (more )
Note: Double labeled: blue - Fgf8 and Uncx.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Strong Regionally restricted 5D , 5D' Strong expression restricted to posterior-most region of presomitic mesoderm.
Specimen 5E: embryonic day 9.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh, Tg(Col1a1-cre)1Bek/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: unsegmented mesenchyme Present Regionally restricted 5E Expression unchanged compared to control littermates.
Specimen 5F,F': embryonic day 10.5; Mbtps1tm1Jdh/Mbtps1tm1Jdh, Tg(Col1a1-cre)1Bek/0 (more )
Note: Conditional mutant. Double labeled: blue - Fgf8 and Uncx.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Absent 5F , 5F' Lack of measurable expression in caudal presomitic mesoderm at E10.5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory