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Gene Expression Data
Assay Details
Assay
Reference: J:310847 Chen H, et al., Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation. J Bone Miner Res. 2014 Dec;29(12):2653-65
Assay type: RT-PCR
MGI Accession ID: MGI:7593885
Gene symbol: Tnfsf11
Gene name: tumor necrosis factor (ligand) superfamily, member 11
Probe: RANKL-pF, RANKL-pR
Probe preparation: labelled with SYBR green
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Actb.
Results Image: 4D RANKL
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
+/+ Appendicular P newborn TS27: limb bone Present Not Specified; total RNA involves: C57BL/6 * SJL Not Specified appendicular (limbs) skeletal elements
deltaE8/deltaE8 Appendicular P newborn TS27: limb bone Weak (a) Not Specified; total RNA involves: C57BL/6 * SJL Runx2tm1Javed/Runx2tm1Javed, Tg(Col2a1-cre)1Bhr/0Not Specified Conditional mutant. appendicular (limbs) skeletal elements
+/+ Axial P newborn TS27: rib
TS27: vertebra 		Present Not Specified; total RNA involves: C57BL/6 * SJL Not Specified axial (rib, spine, tail) skeletal elements
deltaE8/deltaE8 Axial P newborn TS27: rib
TS27: vertebra 		Weak (a) Not Specified; total RNA involves: C57BL/6 * SJL Runx2tm1Javed/Runx2tm1Javed, Tg(Col2a1-cre)1Bhr/0Not Specified Conditional mutant. axial (rib, spine, tail) skeletal elements
Notes:
(a) Significant decreased (60%-80%) expression compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory