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Gene Expression Data
Assay Details
Assay
Reference: J:310847 Chen H, et al., Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation. J Bone Miner Res. 2014 Dec;29(12):2653-65
Assay type: RNA in situ
MGI Accession ID: MGI:7593852
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Probe: Col10a1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3C +/+ upper: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate Present Regionally restricted 3C +/+ upper Expression at proximal end of growth plate was shown.
Specimen 3C +/+ lower: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epiphyseal plate Present Regionally restricted 3C +/+ lower Expression at distal end of growth plate was shown.
Specimen 3C deltaE8/deltaE8 upper: postnatal newborn; Runx2tm1Javed/Runx2tm1Javed, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epiphyseal plate Trace 3C deltaE8/deltaE8 upper Expression was nearly absent in the mutant.
Specimen 3C deltaE8/deltaE8 lower: postnatal newborn; Runx2tm1Javed/Runx2tm1Javed, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: epiphyseal plate Trace 3C deltaE8/deltaE8 lower Expression was nearly absent in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory