Tg(CAG-DsRed,-Wap,-EGFP)14667Lmat
Transgene Detail
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| Symbol: |
Tg(CAG-DsRed,-Wap,-EGFP)14667Lmat |
| Name: |
transgene insertion 14667, Lydia E Matesic |
| MGI ID: |
MGI:7593825 |
| Transgene: |
Tg(CAG-DsRed,-Wap,-EGFP)14667Lmat Location: unknown
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| Alliance: |
Tg(CAG-DsRed,-Wap,-EGFP)14667Lmat page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Mutation details: The transgene construct consists of a chicken beta-actin promoter, a loxP-flanked DsRed2 reporter gene, followed by a mouse full length 2756 bp open reading frame of Wwp1 cDNA and an IRES2-EGFP construct. This transgene expresses the DsRed reporter under the control of the ubiquitous promoter. Upon cre-mediated recombination of loxP sites flanking the DsRed reporter, the mouse Wwp1 gene and the EGFP repoorter are expressed.
(J:250962)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:250962 Basheer WA, et al., Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis. J Mol Cell Cardiol. 2015 Nov;88:1-13 |
| All: |
1 reference(s) |
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Analysis Tools
