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Gene Expression Data
Assay Details
Assay
Reference: J:336871 Toonen JA, et al., A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. PLoS One. 2016;11(5):e0156184
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7587744
Gene symbol: Pou4f2
Gene name: POU domain, class 4, transcription factor 2
Antibody: anti-BRN3B
Detection system: Secondary antibody coupled to Alexa Fluor 546
Results
Specimen S3A: embryonic day 13.5; Adam10tm1Zhu/? (more )
Structure Cell Type Level Pattern Image Note
TS21: neural retinal epithelium retinal ganglion cell Present Regionally restricted S3A Expression in early ganglion cells within basal layer.
Specimen S3B: embryonic day 13.5; Adam10tm1Zhu/Adam10tm1Zhu, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: neural retinal epithelium Present Widespread S3B Expression in all layers in cells that were highly disorganized.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory