About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:237223 Torii H, et al., Septin7 regulates inner ear formation at an early developmental stage. Dev Biol. 2016 Nov 15;419(2):217-228
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7582021
Gene symbol: Septin7
Gene name: septin 7
Antibody: C10C
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1A/E: embryonic day 9.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant. Double labeled: green - Septin7; red - Sox2 (assay MGI:7582026).
Structure Level Pattern Image Note
TS15: neural fold Present Ubiquitous 1E , 1A
TS15: otocyst Present Ubiquitous 1E , 1A
TS15: head mesenchyme Present Regionally restricted 1E , 1A Expressed in the mesenchyme surrounding the otocyst.

Specimen 1B/F: embryonic day 9.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant. Double labeled: green - Septin7; red - Sox2 (assay MGI:7582026).
Structure Level Pattern Image Note
TS15: otocyst Absent 1F , 1B
TS15: neural fold Present 1B , 1F Similar as in the control.
TS15: head mesenchyme Present Regionally restricted 1B , 1F Expressed in the mesenchyme surrounding the otocyst, similar as in the control.

Specimen 5A/E: embryonic day 13.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant. Double labeled: green - Septin7; red - Sox2 (assay MGI:7582026).
Structure Level Pattern Image Note
TS21: inner ear epithelium Present 5E , 5A

Specimen 5B/F: embryonic day 13.5; Foxg1tm1(cre)Skm/Foxg1+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant. Double labeled: green - Septin7; red - Sox2 (assay MGI:7582026).
Structure Level Pattern Image Note
TS21: inner ear epithelium Absent 5B , 5F

Specimen 7A: embryonic day 15.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: inner ear epithelium Present 7A

Specimen 7B: embryonic day 15.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cochlea epithelium Absent 7B

Specimen 9A: embryonic day 18.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: inner ear epithelium Present 9A

Specimen 9B: embryonic day 18.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cochlea epithelium Absent 9B

Specimen not shown: embryonic day 13.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: inner ear epithelium Present

Specimen not shown: embryonic day 13.5; Emx2tm2(cre)Sia/Emx2+, Septin7tm1Ksh/Septin7tm1Ksh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: cochlea epithelium Present Regionally restricted Expressed in some of the cells (the deletion was not completed).


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory