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Gene Expression Data
Assay Details
Assay
Reference: J:333825 Lorenzana-Carrillo MA, et al., TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure. Sci Transl Med. 2022 Nov 2;14(669):eabm3565
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7581055
Gene symbol: Tnni3
Gene name: troponin I, cardiac 3
Antibody: Anti-Cardiac Troponin I antibody [EP1106Y] (ab52862)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S6B: postnatal adult; Pkmtm1.1Mgvh/Pkmtm1.1Mgvh, Tg(Myh6-cre)2182Mds/0 (more )
Note: Conditional mutant. Triple labeled: magenta - Tnni3; green - TUNEL; red - WGA.
Structure Cell Type Level Pattern Image Note
TS28: myocardium layer cardiac muscle cell Present S6B More TUNEL positive staining in the Troponin I positive cardiomyocytes in the mutant.
Specimen not shown: postnatal adult; Tg(Myh6-cre)2182Mds/0 (more )
Structure Cell Type Level Pattern Image Note
TS28: myocardium layer cardiac muscle cell Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory