Gsdma3tm1.1Lty
Targeted Allele Detail
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| Symbol: |
Gsdma3tm1.1Lty |
| Name: |
gasdermin A3; targeted mutation 1.1, Liang-Tung Yang |
| MGI ID: |
MGI:7580972 |
| Synonyms: |
Gsdma3fx |
| Gene: |
Gsdma3 Location: Chr11:98517186-98529052 bp, + strand Genetic Position: Chr11, 62.21 cM
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| Alliance: |
Gsdma3tm1.1Lty page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:335519
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Conditional ready) |
| Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked neomycin selection cassette and second loxP site were inserted downstream of exon 7. The neomycin selection cassette was removed via flp-mediated recombination leaving exons 2-7 floxed.
(J:335519)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gsdma3 Mutation: |
30 strains or lines available
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| Original: |
J:335519 Huang LY, et al., Gasdermin A Is Required for Epidermal Cornification during Skin Barrier Regeneration and in an Atopic Dermatitis-like Model. J Invest Dermatol. 2023 Mar 24; |
| All: |
1 reference(s) |
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