Gene Expression Data
Assay Details
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Assay
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Reference:
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J:299546
Yahya I, et al., Cxcr4 and Sdf-1 are critically involved in the formation of facial and non-somitic neck muscles. Sci Rep. 2020 Mar 19;10(1):5049
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7580591
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Gene symbol:
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Msc
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Gene name:
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musculin
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Probe:
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Msc probe
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Probe preparation:
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labelled with digoxigenin RNA
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Results
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Specimen
1aG:
embryonic day 10.5
(more  )
Specimen
1aG:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: 2nd branchial arch |
Present |
Regionally restricted |
1aG
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Expression in undifferentiated facial muscle progenitor cells
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Specimen
1aH:
embryonic day 10.5
(more )
Specimen
1aH:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section from whole mount
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Specimen
1aI:
embryonic day 12.5
(more )
Specimen
1aI:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: skeletal muscle |
Present |
Regionally restricted |
1aI
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Expression individual BA2-derived muscle.
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Specimen
1bC:
embryonic day 12.5
(more )
Specimen
1bC:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: skeletal muscle |
Present |
Regionally restricted |
1bC
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Expression individual BA2-derived muscle.
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Specimen
2A:
embryonic day 14.5
(more )
Specimen
2A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: masseter |
Strong |
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2A
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Expression in BA1-derived muscle. No noticeable difference between genotypes.
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| TS22: temporalis |
Strong |
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2A
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Expression in BA1-derived muscle. No noticeable difference between genotypes.
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| TS22: facial muscle |
Present |
Regionally restricted |
2A
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The following BA2-derived muscle were identifiable: buccinator, zyzomaticus, quadratus labii, frontalis, orbicularis oculi, auricularis and occipitalis.
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| TS22: sterno-mastoid |
Present |
Regionally restricted |
2A
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Expression in on-somitic neck muscles such as trapezius, sternocleidomastoid and splenius.
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| TS22: trapezius |
Present |
Regionally restricted |
2A
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Expression in on-somitic neck muscles such as trapezius, sternocleidomastoid and splenius.
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Specimen
2B:
embryonic day 14.5; Cxcr4tm1Yzo/Cxcr4 +
(more )
Specimen
2B:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Cxcr4tm1Yzo/Cxcr4+
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: masseter |
Strong |
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2B
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Expression in BA1-derived muscle. No noticeable difference between genotypes.
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| TS22: temporalis |
Strong |
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2B
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Expression in BA1-derived muscle. No noticeable difference between genotypes.
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| TS22: facial muscle |
Weak |
Regionally restricted |
2B
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BA2-derived muscle partially reduced in heterozygotes.
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| TS22: sterno-mastoid |
Weak |
Regionally restricted |
2B
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Non-somitic neck muscles such as trapezius, sternocleidomastoid and part of splenius were were less developed compared to wild type.
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| TS22: trapezius |
Weak |
Regionally restricted |
2B
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Non-somitic neck muscles such as trapezius, sternocleidomastoid and part of splenius were were less developed compared to wild type.
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Specimen
2C:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Cxcr4tm1Yzo/Cxcr4tm1Yzo
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: masseter |
Strong |
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2C
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BA1- derived muscles were clearly visible and unaffected compared to wild type and heterozygote.
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| TS22: temporalis |
Strong |
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2C
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BA1- derived muscles were clearly visible and unaffected compared to wild type and heterozygote.
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| TS22: facial muscle |
Weak |
Regionally restricted |
2C
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BA2-derived muscle were considerably less developed compared to wild type and heterozygotes, leading to reduced expression domain in this area.
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| TS22: sterno-mastoid |
Trace |
Regionally restricted |
2C
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Non-somitic neck muscles such as trapezius, sternocleidomastoid and splenius were nearly completely missing.
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| TS22: trapezius |
Trace |
Regionally restricted |
2C
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Non-somitic neck muscles such as trapezius, sternocleidomastoid and splenius were nearly completely missing.
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Analysis Tools