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Gene Expression Data
Assay Details
Assay
Reference: J:304350 Carley E, et al., The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation. Elife. 2021 Mar;:e58541
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7580408
Gene symbol: Flg
Gene name: filaggrin
Antibody: anti-Filaggrin
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S3 Figure 2E WT: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: epidermis keratinocyte Present S3 Figure 2E WT Expression is in granular and cornified keratinocyte layers.
Specimen S3 Figure 2E dKO: embryonic day 15.5; Sun1tm1Mhan/Sun1tm1Mhan, Sun2tm1Mhan/Sun2tm1Mhan (more )
Structure Cell Type Level Pattern Image Note
TS23: epidermis keratinocyte Present S3 Figure 2E Sun dKO Expression in granular and cornified keratinocyte layers in this mutant has expanded compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory