Tg(Pcp2-Rreb1)20Slac
Transgene Detail
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Symbol: |
Tg(Pcp2-Rreb1)20Slac |
Name: |
transgene insertion 20, Susan L Ackerman |
MGI ID: |
MGI:7579318 |
Synonyms: |
Tg(PCP2-Rreb1/3xV5)20/J |
Transgene: |
Tg(Pcp2-Rreb1)20Slac Location: unknown
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Alliance: |
Tg(Pcp2-Rreb1)20Slac page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Pcp2-Rreb1)20Slac expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Rreb1 (MGI:2443664) |
V7 cDNA of Rreb1with triple C-terminal V5 tags |
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Tg(Pcp2-Rreb1)20Slac expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Pcp2 (MGI:97508) |
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Mutation details: The V7 cDNA of Rreb1with triple C-terminal V5 tags was inserted into the BamH1 site of the fourth exon of the L7/Pcp2 minigene, such that the mouse Pcp2 promoter drives expression of the V7 transcript, and this randomly inserted into the genome after injection into the pronucleus of a C57BL/6J zygote.
(J:344394)
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Inheritance: |
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Not Specified |
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:344394 Cazzaro S, et al., Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2217128120 |
All: |
1 reference(s) |
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