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Tg(Pcp2-Rreb1)20Slac
Transgene Detail
Summary
Symbol: Tg(Pcp2-Rreb1)20Slac
Name: transgene insertion 20, Susan L Ackerman
MGI ID: MGI:7579318
Synonyms: Tg(PCP2-Rreb1/3xV5)20/J
Transgene: Tg(Pcp2-Rreb1)20Slac  Location: unknown  
Alliance: Tg(Pcp2-Rreb1)20Slac page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Pcp2-Rreb1)20Slac expresses 1 gene
 
Tg(Pcp2-Rreb1)20Slac expression driven by 1 gene
 
Mutation detailsThe V7 cDNA of Rreb1with triple C-terminal V5 tags was inserted into the BamH1 site of the fourth exon of the L7/Pcp2 minigene, such that the mouse Pcp2 promoter drives expression of the V7 transcript, and this randomly inserted into the genome after injection into the pronucleus of a C57BL/6J zygote. (J:344394)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:344394 Cazzaro S, et al., Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2217128120
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory