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Gene Expression Data
Assay Details
Assay
Reference: J:88676 Hammer F, et al., Transcriptional regulation of P450scc gene expression in the embryonic rodent nervous system. Endocrinology. 2004 Feb;145(2):901-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7579189
Gene symbol: Sp1
Gene name: trans-acting transcription factor 1
Antibody: anti-Sp1
Detection system: Secondary antibody coupled to Alexa Fluor 350
Results
Specimen 8 Sp1 Cortex: embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 8_Cortex Merged , 8_Cortex Sp1 Co-localization of expression with Cyp11a1 and Sp4 in molecular layer of neocortex.
TS26: cortical plate Present 8_Cortex Merged , 8_Cortex Sp1 Co-localization of expression with Cyp11a1 and Sp4 in cortical plate.

Specimen 8 Sp1 Hippocampus: embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Level Pattern Image Note
TS26: hippocampus Present 8_Hippocampus Sp1 , 8_Hippocampus Merged Co-localization of expression with Cyp11a1 and Sp4 in hippocampal neuroeipithelium.

Specimen 8 Sp1 Cerebellum: embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Level Pattern Image Note
TS26: cerebellum Purkinje cell layer Present 8_Cerebellum Merged , 8_Cerebellum Sp1 Co-localization of expression with Cyp11a1 and Sp4 in Purkinje cell layer of cerebellum.

Specimen 8 Sp1 Retina: embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Cell Type Level Pattern Image Note
TS26: retina ganglion cell layer Present 8_Retina Sp1 , 8_Retina Merged Co-localization of expression with Cyp11a1 and Sp4 in ganglion cell layer and inner nuclear layer
TS26: retina inner nuclear layer Present 8_Retina Sp1 , 8_Retina Merged Co-localization of expression with Cyp11a1 and Sp4 in ganglion cell layer and inner nuclear layer
TS26: retina amacrine cell Present 8_Retina Sp1 , 8_Retina Merged Co-localization of expression with Cyp11a1 and Sp4 in amacrine cells of retina.

Specimen 8 Sp1 Pituitary: embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Level Pattern Image Note
TS26: pituitary gland Present 8_Pituitary Merged , 8_Pituitary Sp1 Co-localization of expression with Cyp11a1 and Sp4 in pituitary primordium.

Specimen 9 Sp1 Trigeminal Ganglion (upper): embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Level Pattern Image Note
TS26: trigeminal ganglion Present 9_Trigeminal Ganglion Sp1 (upper) , 9_Trigeminal Ganglion Merged (upper) Co-localization of expression with Cyp11a1 and Sp4 in trigeminal ganglia

Specimen 9 Sp1 Trigeminal Ganglion (lower): embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Cell Type Level Pattern Image Note
TS26: trigeminal ganglion neuron Present 9_Trigeminal Ganglion Sp1 (lower) , 9_Trigeminal Ganglion Merged (lower) Co-localization of expression with Cyp11a1 and Sp4 in neurons.

Specimen 9 Sp1 Dorsal Root Ganglion: embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Level Pattern Image Note
TS26: dorsal root ganglion Present 9_Dorsal Root Ganglion Sp1 , 9_Dorsal Root Ganglion Merged Co-localization of expression with Cyp11a1 and Sp4 in dorsal root ganglia.

Specimen 9 Sp1 Whiskers: embryonic day 18.5 (more )
Note: Triple labeled: blue - Sp1; green - Cyp11a1 (assay MGI:7579184); red - Sp4 (assay MGI:7579191).
Structure Level Pattern Image Note
TS26: vibrissa outer root sheath Present 9_Whiskers Sp1 , 9_Whiskers Merged Co-localization of expression with Cyp11a1 in external root sheath.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory