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Gene Expression Data
Assay Details
Assay
Reference: J:332929 Harnett D, et al., A critical period of translational control during brain development at codon resolution. Nat Struct Mol Biol. 2022 Dec;29(12):1277-1290
Assay type: RNA in situ
MGI Accession ID: MGI:7579033
Gene symbol: Satb2
Gene name: special AT-rich sequence binding protein 2
Probe: Mm-Satb2 (413261)
Probe preparation: Antisense DNA
Visualized with: Fluorescence
Results
Specimen 2d E12.5 mRNA Satb2: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: neocortex Strong Widespread 2d E12.5 mRNA Merge , 2d E12.5 mRNA Satb2 Authors report robust expression throughout neocortex.
TS20: cerebral cortex ventricular layer neural progenitor cell Present Regionally restricted 2d E12.5 mRNA Satb2 , 2d E12.5 mRNA Merge Expression in ventricular zone in multipotent neural progenitors.
TS20: cortical plate neuron Present Clusters 2d E12.5 mRNA Merge , 2d E12.5 mRNA Satb2 Expression throughtout nascent cortical plate in early born post-mitotic neurons, almost half of clusters colocalizing with Bcl11b.
Specimen 2d E14.5 mRNA Satb2: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neocortex Present Regionally restricted 2d E14.5 mRNA Merge , 2d E14.5 mRNA Satb2
Specimen 2d E16.5 mRNA Satb2: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: neocortex neuron Present Regionally restricted 2d E16.5 mRNA Satb2 , 2d E16.5 mRNA Merge Broadly expressed by E16.5. Neurons that have migrated to upper layers almost exclusively express Satb2.
Specimen ED3a FISH Satb2+/+ Satb2 (upper): embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: neocortex Present Regionally restricted ED3a FISH Satb2+/+ Satb2 (upper)
Specimen ED3a FISH Satb2+/+ Satb2 (lower): embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cortical plate Present ED3a FISH Satb2+/+ Satb2 (lower)
Specimen ED3a FISH Satb2-/- Satb2 (lupper): embryonic day 14.5; Satb2tm1(cre)Vit/Satb2tm1(cre)Vit (more )
Structure Level Pattern Image Note
TS22: neocortex Absent ED3a FISH Satb2-/- Satb2 (upper)
Specimen ED3a FISH Satb2-/- Satb2 (llowerr): embryonic day 14.5; Satb2tm1(cre)Vit/Satb2tm1(cre)Vit (more )
Structure Level Pattern Image Note
TS22: cortical plate Absent ED3a FISH Satb2-/- Satb2 (lower)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory