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Gene Expression Data
Assay Details
Assay
Reference: J:93057 Schuurmans C, et al., Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J. 2004 Jul 21;23(14):2892-902
Assay type: RNA in situ
MGI Accession ID: MGI:7578996
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe
Probe preparation: Antisense RNA
Results
Specimen S1A: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex ventricular layer neural progenitor cell Present S1A Expressed in dorsal telencephalic progenitors.
TS21: cortical preplate Absent S1A
Specimen S1B: embryonic day 13.5; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex ventricular layer neural progenitor cell Present S1B Similar as in the wild-type.
TS21: cortical preplate Present S1B Ectopic expression in the mutant.
Specimen S1C: embryonic day 13.5; Neurog1tm1And/Neurog1tm1And, Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex ventricular layer neural progenitor cell Present S1C Similar as in the wild-type.
TS21: cortical preplate Present S1C Ectopic expression in the mutant.
Specimen not shown WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: telencephalon Present
Specimen not shown Ngn2-/-: embryonic day 15.5; Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Similar as in the wild-type.
Specimen not shown Ngn1-/-;Ngn2-/-: embryonic day 15.5; Neurog1tm1And/Neurog1tm1And, Neurog2tm2Fgu/Neurog2tm2Fgu (more )
Structure Level Pattern Image Note
TS23: telencephalon Present Similar as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory