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Gene Expression Data
Assay Details
Assay
Reference: J:316178 Gamart J, et al., SMAD4 target genes are part of a transcriptional network that integrates the response to BMP and SHH signaling during early limb bud patterning. Development. 2021 Dec 1;148(23):dev200182
Assay type: RNA in situ
MGI Accession ID: MGI:7576860
Gene symbol: Alx4
Gene name: aristaless-like homeobox 4
Probe: Alx4 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6D Alx4 WT: embryonic day 10.0; Tg(Prrx1-cre)1Cjt/0 (more )
Structure Level Pattern Image Note
TS16: forelimb bud Present 6D Alx4 WT
Specimen 6D Alx4 delta/deltac: embryonic day 10.0; Smad4tm2.1Cxd/Smad4tm2.2Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: forelimb bud Weak Regionally restricted 6D Alx4 delta/deltac Expression reduced and altered compared to control.
Specimen S5B Alx4 E10.5 WT: embryonic day 10.5; Tg(Prrx1-cre)1Cjt/0 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present S5B Alx4 WT
Specimen S5B Alx4 E10.5 delta/deltac: embryonic day 10.5; Smad4tm2.1Cxd/Smad4tm2.2Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Present Regionally restricted S5B Alsx4 delta/deltac Authors report differential expression compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory