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Gene Expression Data
Assay Details
Assay
Reference: J:131173 Liu Y, et al., Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development. 2008 Feb;135(3):579-88
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7573002
Gene symbol: Cdkn2b
Gene name: cyclin dependent kinase inhibitor 2B
Antibody: anti-p15Ink4b
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 9A/B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal cartilage Absent 9A/B
TS23: perichondrium Absent 9A/B
Specimen 9C/D: embryonic day 15.5; Zeb1tm2Yhi/Zeb1tm2Yhi (more )
Structure Level Pattern Image Note
TS23: nasal cartilage Present 9C/D Ectopically expressed in the mutant.
TS23: perichondrium Present 9C/D Ectopically expressed in the mutant.
Specimen 9E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon ventricular layer Absent 9E
Specimen 9F: embryonic day 15.5; Zeb1tm2Yhi/Zeb1tm2Yhi (more )
Structure Level Pattern Image Note
TS23: diencephalon ventricular layer Present 9F Ectopically expressed in the mutant.
Specimen 9H/I: embryonic day 15.5; Zeb1tm2Yhi/Zeb1tm2Yhi (more )
Note: Double labeled: red - Cdkn2b; green - BrdU.
Structure Level Pattern Image Note
TS23: diencephalon ventricular layer Present 9I , 9H Ectopically expressed in the mutant. Overlapping with BrdU incorporation was seen, but there were a number of additional positive cells in this region that were BrdU-negative.
Specimen S5A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: skin Present S5A
TS23: nasal cartilage Absent S5A
TS23: perichondrium Absent S5A
Specimen S3B: embryonic day 15.5; Zeb1tm2Yhi/Zeb1tm2Yhi (more )
Structure Level Pattern Image Note
TS23: skin Present S5B Similar as in the wild-type.
TS23: nasal cartilage Present S5B Ectopically expressed in the mutant.
TS23: perichondrium Present S5B Ectopically expressed in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory