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Gene Expression Data
Assay Details
Assay
Reference: J:137018 Voss AK, et al., C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment. Development. 2008 Jun;135(12):2139-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7572987
Gene symbol: Reln
Gene name: reelin
Antibody: G10
Results
Specimen 5A: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex marginal layer Cajal-Retzius cell Strong 5A Immunoreactivity was evenly spaced.

Specimen 5B: embryonic day 13.5; Rapgef1Gt(pGT1.8geo)5Pgr/Rapgef1Gt(pGT1.8geo)5Pgr (more )
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex marginal layer Cajal-Retzius cell Strong 5B Immunoreactivity was detected but was unevenly spaced in the mutant, congregated in some areas and absent in other areas.

Specimen 5E: embryonic day 12.5 (more )
Note: Double labeled: green - Reln; red - Laminin.
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex marginal layer Cajal-Retzius cell Present 5E

Specimen 5F: embryonic day 12.5; Rapgef1Gt(pGT1.8geo)5Pgr/Rapgef1Gt(pGT1.8geo)5Pgr (more )
Note: Double labeled: green - Reln; red - Laminin.
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex marginal layer Cajal-Retzius cell Present 5F The gaps in Reln-positive Cajal-Retzius cell spacing corresponded to the disruption of the C3G<gt/gt> laminin-positive basement membrane in the mutant cortex.

Specimen 5G: embryonic day 13.5 (more )
Note: Double labeled: green - Reln; red - Laminin.
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex marginal layer Cajal-Retzius cell Present 5G

Specimen 5H: embryonic day 13.5; Rapgef1Gt(pGT1.8geo)5Pgr/Rapgef1Gt(pGT1.8geo)5Pgr (more )
Note: Double labeled: green - Reln; red - Laminin.
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex marginal layer Cajal-Retzius cell Present 5H The gaps in Reln-positive Cajal-Retzius cell spacing corresponded to the disruption of the C3G<gt/gt> laminin-positive basement membrane in the mutant cortex.

Specimen 5I: embryonic day 14.5 (more )
Note: Double labeled: green - Reln; red - Laminin.
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex marginal layer Cajal-Retzius cell Present 5I

Specimen 5J: embryonic day 14.5; Rapgef1Gt(pGT1.8geo)5Pgr/Rapgef1Gt(pGT1.8geo)5Pgr (more )
Note: Double labeled: green - Reln; red - Laminin.
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex marginal layer Cajal-Retzius cell Present 5J The gaps in Reln-positive Cajal-Retzius cell spacing corresponded to the disruption of the C3G<gt/gt> laminin-positive basement membrane in the mutant cortex.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory