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Gene Expression Data
Assay Details
Assay
Reference: J:320323 Bin G, et al., Aire promotes the self-renewal of embryonic stem cells through Lin28. Stem Cells Dev. 2012 Oct 10;21(15):2878-90
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7571539
Gene symbol: Aire
Gene name: autoimmune regulator
Antibody: AIRE Monoclonal Antibody (5H12), eFluor 660
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5B Wt: postnatal adult (more )
Note: Double labeled: green - Aire; red - Lin28a (assay MGI:7571541).
Structure Level Pattern Image Note
TS28: primary oocyte Present 5B Wt Merge , 5B Wt Aire
Specimen 5B Mut: postnatal adult; Airetm1.1Doi/Airetm1.1Doi (more )
Note: Double labeled: green - Aire; red - Lin28a (assay MGI:7571541).
Structure Level Pattern Image Note
TS28: primary oocyte Absent 5B Mut Aire , 5B Mut Merge
Specimen 5C 1-cell: embryonic day 0.5 (more )
Note: Double labeled: green - Aire; red - Lin28a (assay MGI:7571541).
Structure Level Pattern Image Note
TS1: 1-cell stage embryo Present 5C 1-cell Merge , 5C 1-cell Aire Expressed in the cytoplasm. Foci-shaped colocalization with Lin28a was seen.
Specimen 5C 2-cell: embryonic day 1.5 (more )
Note: Double labeled: green - Aire; red - Lin28a (assay MGI:7571541).
Structure Level Pattern Image Note
TS2: 2-cell stage embryo Present 5C 2-cell Aire , 5C 2-cell Merge Expressed in the cytoplasm. Foci-shaped colocalization with Lin28a was seen.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory