Tg(ACTA1-Sspn)28Rcros
Transgene Detail
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| Symbol: |
Tg(ACTA1-Sspn)28Rcros |
| Name: |
transgene insertion 28, Rachelle H Crosbie-Watson |
| MGI ID: |
MGI:7571427 |
| Synonyms: |
mSSPN-Tg |
| Transgene: |
Tg(ACTA1-Sspn)28Rcros Location: unknown
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| Alliance: |
Tg(ACTA1-Sspn)28Rcros page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(ACTA1-Sspn)28Rcros expresses
1 gene
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Tg(ACTA1-Sspn)28Rcros expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
ACTA1 (58) |
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Mutation details: A human skeletal actin promoter and VP1 intron drives expression of a full-length mouse Sspn cDNA. Four viable lines were recovered (Lines 28, 23, 32 and 15). Line 28 showed highest expression and was chosen for further analysis.
(J:239326)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:239326 Gibbs EM, et al., High levels of sarcospan are well tolerated and act as a sarcolemmal stabilizer to address skeletal muscle and pulmonary dysfunction in DMD. Hum Mol Genet. 2016 Dec 15;25(24):5395-5406 |
| All: |
3 reference(s) |
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Analysis Tools
