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Gene Expression Data
Assay Details
Assay
Reference: J:67383 Britsch S, et al., The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev. 2001 Jan 1;15(1):66-78
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7569223
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-Tubulin beta 3 (clone TUJ1, MMS-435P/801202)
Detection system: Secondary antibody coupled to Cy2
Results
Specimen 4b: embryonic day 11.5 (more )
Note: Double labeled: green - Tubb3; red - Fabp7 (assay MGI:7569222).
Structure Cell Type Level Pattern Image Note
TS19: dorsal root ganglion neuron Present 4b
TS19: future spinal cord neuron Present 4b
TS19: spinal nerve neuron Present 4b
Specimen 4d: embryonic day 11.5; Sox10Dom/Sox10Dom (more )
Note: Double labeled: green - Tubb3; red - Fabp7 (assay MGI:7569222).
Structure Cell Type Level Pattern Image Note
TS19: dorsal root ganglion neuron Present 4d Dorsal root ganglia formed broad fusions with the lateral neural tube, which contained, inappropriately, neurons.
TS19: future spinal cord neuron Present 4d
TS19: spinal nerve neuron Present 4d
Specimen 4f: embryonic day 11.5; Erbb3tm2Cbm/Erbb3tm2Cbm (more )
Note: Double labeled: green - Tubb3; red - Fabp7 (assay MGI:7569222).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 4f
TS19: future spinal cord Present 4f
TS19: spinal nerve Present 4f
Specimen 5c: embryonic day 12.5 (more )
Note: Double labeled: green - Tubb3; red - Fabp7 (assay MGI:7569222).
Structure Cell Type Level Pattern Image Note
TS20: dorsal root ganglion neuron Present 5c
TS20: spinal cord neuron Present 5c
Specimen 5h: embryonic day 12.5; Sox10Dom/Sox10Dom (more )
Note: Double labeled: green - Tubb3; red - Fabp7 (assay MGI:7569222).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord neuron Present 5h
TS20: dorsal root ganglion neuron Present 5h Marked reduction in size (affected a major proportion of the neurons) compared with the wild-type. Dorsal root ganglia formed broad fusions with the lateral neural tube, which contained, inappropriately, neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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