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Gene Expression Data
Assay Details
Assay
Reference: J:225226 Dykes IM, et al., HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region. Circ Res. 2014 Jun 20;115(1):23-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7569170
Gene symbol: Hic2
Gene name: hypermethylated in cancer 2
Antibody: anti-HIC2 (AB84899)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2P: embryonic day 13.5; Hic2Gt(RRN127)Byg/Hic2+ (more )
Structure Level Pattern Image Note
TS21: heart Present Widespread 2P
Specimen 2Q: embryonic day 13.5; Hic2Gt(RRN127)Byg/Hic2+ (more )
Structure Level Pattern Image Note
TS21: heart ventricle wall Present 2Q
TS21: cardiac muscle tissue Present Widespread 2Q Expression throughout myocardium but concentrated at specific points.
Specimen 2S/T: embryonic day 9.5; Hic2Gt(RRN127)Byg/Hic2+ (more )
Note: Double labeled: red - Hic2; green - Ctbp1 (assay MGI:7569174).
Structure Cell Type Level Pattern Image Note
TS15: cardiac muscle tissue Present Regionally restricted 2S , 2T Co-expressed with Ctbp1 in myocardium.
TS15: blood erythrocyte Absent 2T , 2S
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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