About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:272567 Aires R, et al., Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes. Dev Cell. 2019 Feb 11;48(3):383-395.e8
Assay type: RNA in situ
MGI Accession ID: MGI:7568802
Gene symbol: Lin28b
Gene name: lin-28 homolog B
Probe: Lin28b cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5Bb: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: tail neural tube Present Regionally restricted 5Bb inset , 5Bb Expressed in the caudal part.
TS17: tail mesenchyme Present Regionally restricted 5Bb , 5Bb inset Expressed in the ventral mesoderm adjacent the neural tube.

Specimen 5Bf: embryonic day 10.5; Gdf11tm1Sjl/Gdf11tm1Sjl (more )
Structure Level Pattern Image Note
TS17: tail mesenchyme Present 5Bf , 5Bf inset Stronger expression compared with the wild-type.
TS17: tail neural tube Present 5Bf , 5Bf inset Stronger expression compared with the wild-type.

Specimen 5Bj: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme Weak Regionally restricted 5Bj , 5Bj inset Strongly down-regulated expression in the entire tail region. An absence of any detectable transcripts in the tip region was seen.
TS19: tail neural tube Weak Regionally restricted 5Bj , 5Bj inset Strongly down-regulated expression in the entire tail region. An absence of any detectable transcripts in the tip region was seen.

Specimen 5Bn: embryonic day 11.5; Gdf11tm1Sjl/Gdf11tm1Sjl (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme Strong 5Bn inset , 5Bn Remained robustly expressed.
TS19: tail neural tube Strong 5Bn inset , 5Bn Remained robustly expressed.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory