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Gene Expression Data
Assay Details
Assay
Reference: J:343078 Diniz F, et al., Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance. Nat Commun. 2023 Nov 25;14(1):7733
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7567409
Gene symbol: Acly
Gene name: ATP citrate lyase
Antibody: anti-Acly (1542)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S9a: postnatal day 0; Aclytm1.1Welk/Acly+ (more )
Note: Triple labeled: green - Acly; white - cytokeratin; red - recombinase reporter.
Structure Level Pattern Image Note
TS27: metanephros Present S9a
Specimen S9c: postnatal day 0; Aclytm1.1Welk/Acly+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Acly; white - cytokeratin; red - recombinase reporter.
Structure Level Pattern Image Note
TS27: metanephros Present S9c
Specimen S9e: postnatal day 0; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Acly; white - cytokeratin; red - recombinase reporter.
Structure Level Pattern Image Note
TS27: nephrogenic interstitium Absent S9e No expression in nephrogenic lineage.
TS27: metanephros Present Regionally restricted S9e Expression in ureteric bud lineage.
Specimen S9g: postnatal day 0; Aclytm1.1Welk/Aclytm1.1Welk, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Acly; white - cytokeratin; red - recombinase reporter.
Structure Level Pattern Image Note
TS27: nephrogenic interstitium Absent S9g No expression in nephrogenic lineage.
TS27: metanephros Present Regionally restricted S9g Expression in colocalized with cytokeratin expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory